Hand of Horror

Golden Age Origin
The Hand of Horror was a large mechanical robot hand/gauntlet created by the genius inventor known as Crimesmith to kill his enemies. It had superhuman strength (sufficients to rip apart steel bars, and could leap at least six feet in the air. It could also wield weapons such as knives and guns.  It generally strangled people to death, but also had slashing talons.  Crimesmith was able to control the Hand from a distance, but at times, it seemed to act autonomously or semi-autonomously.

Golden Age Appearances
Feature Comics #107